IHT Special: Women Face Fight to Keep Their Rights in Tunisia







TUNIS — At the funeral this month of Chokri Belaid, the murdered secular opposition leader in Tunisia, his widow Basma Khalfaoui, a prominent feminist, stood on the ambulance carrying his casket, her head uncovered, raising her arm to wave a defiant victory sign.




“My husband was denouncing Ennahda’s double talk and we will continue his struggle,” Ms. Khalfaoui, 42, said at the funeral, referring to the moderate Islamist party that governs the country. “We will not give up the fight.”


Tunisia, perceived by the West as the most secular country in the Arab world and a staunch promoter of women’s rights, has gone through a rocky transition since the revolution two years ago that ousted President Zine el-Abidine Ben Ali. While political pluralism exists for the first time in decades, new freedoms for some are threatening long-cherished ones for others — in particular those for Tunisian women.


After Tunisia gained its independence from France in 1956, the government passed laws to expand women’s rights, including the right to education and gender equality. Over the following decades, Islamists were persecuted and exiled while the government pushed the secularization of society to such an extent that a decree in 1981 banned women from wearing a veil in public buildings and universities.


After the fall of Mr. Ben Ali’s regime, the Ennahda party won elections in October 2011 with a comfortable majority. Since then, worries have grown that one of its aims is to restrict women’s freedoms in a country where, until recently, those rights had been taken for granted for decades.


“I think it’s normal that the Islamists are so vocal — veiled women used to be harassed and the frustration came out all at once,” said Sarah Ben Hamadi, 28, a blogger and journalist. “We are simply paying today for Ben Ali’s mistakes.”


“I don’t think the country is more radical,” she added. “There is more freedom so we see more of the religious people who were hiding in the past.”


Certainly, the religious ultraconservatives known as Salafists are more visible. The University of Manouba, in suburban Tunis, experienced months of tension last year after Salafist students rioted against the ban on the niqab, the face-covering veil.


More worrying are legal overhauls, human rights officials say. As Tunisia’s Constituent Assembly writes a new constitution, there have been repeated confrontations between Islamists, who dominate the assembly and want to roll back some rights acquired by women, and secular liberals, who want an expansion of those rights to include, for example, equal inheritance rights.


“We cannot speak of an obvious rollback since the legal reality is still the same,” said Amna Guellali, the director of Human Rights Watch in Tunis. “But acquired rights are being threatened by repeated attacks by Salafist groups on those they consider infidels or on behavior they deem contrary to Islamic morality.”


When a young woman was allegedly raped by police officers in September, she was charged with indecency and risked six months in prison before the charges were dropped, after a huge uproar. Human rights organizations cite the case as an example of how rights are under threat.


“Under the old regime, there were similar cases,” Ms. Guellali acknowledged. “Now with the new freedoms in the country, the media is paying attention to these kinds of stories.” Still, she said, even allowing for the amplifying effect of the news coverage, something has changed.


Chema Gargouri, the president of the Tunisian Association for Management and Social Stability, a nongovernmental organization that provides training and microloans for women and young people in poor areas, said women were more secure under Mr. Ben Ali.


“What was really striking to me after the revolution was that women started to lose their self-esteem,” Ms. Gargouri said. “The dictatorship was pro-woman. The hatred against the dictatorship is expressed through action against women.”


The rise of social and religious repression and the loss of self-confidence “prevents any entrepreneurial initiative for women,” she added.


Ms. Gargouri, who is in her 40s, said that women of her generation had never previously had to debate or defend their rights. But recent developments had pushed her to work to raise awareness of the challenge now facing them.


“What scares me is that the Tunisian woman seems lost,” she said. “In many places I go to, people ask what the government can do for them. We try to teach them to do it on their own.”


The fact is that Tunisia has an Islamist majority, said Ms. Ben Hamadi, the blogger. “Article 1 of the Tunisian Constitution states that it is an Islamic state,” she said. “If we want real democracy, we must listen to everyone’s voice.”


Read More..

Bits Blog: Marissa Mayer Puts Her Stamp on Yahoo.com

8:39 a.m. | Updated On Wednesday, Yahoo introduced a fresh new home page with Marissa Mayer’s stamp all over it.

Yahoo’s home page has long been a sort of sad reflection of the company. A jazzed-up Craigslist of sorts, the site was often cluttered with low-quality ads and irrelevant content and in no way reflected the fact that Yahoo is one of the most visited sites on the Web. With more than 700 million monthly visitors, Yahoo is still a leading source of information for sports, finance and entertainment.

Ms. Mayer took the reins as Yahoo’s chief executive last July. Before that she was a long-time executive at Google, where she was widely credited with the simple look of the Google search page. Now she seeks to apply that same, clean aesthetic to one of the most chaotic sites on the Web.

In an interview Tuesday, Ms. Mayer said she wanted to make Yahoo’s site “fresh and dynamic and add an element of surprise and serendipity.”

Gone are the low-quality ads. She has added an infinite, Twitter-like news feed and a stream of content recommended by users’ Facebook friends. Instead of trying to jam every Yahoo feature onto the site, the new design gives special prominence to Yahoo’s most popular Web properties: Yahoo’s e-mail and news service, Yahoo Finance, Yahoo Sports, its movie listing site and OMG, its popular entertainment site.

Users can now easily share content they see on the home page via e-mail, Twitter or Facebook with one click. They also have limited ability to customize the site to their liking. They can turn off home page features like horoscopes, stock quotes and sports stats. Ms. Mayer pointed out that the more items users switch on and off, the smarter the Yahoo algorithm gets and the more relevant content Yahoo will serve up.

Yahoo’s redesigned home page is the third major aesthetic improvement Ms. Mayer has introduced since joining the company. In December, she redesigned Yahoo’s e-mail service and its once-popular photo-sharing service Flickr.

In the interview, Ms. Mayer said these would be the “first of many releases” and she would turn her focus to a dozen or more Yahoo products. Her next priority for the home page, she said, will be adding content sources. In December, Yahoo signed three deals, with CBS Television, NBC Sports and ABC News. In each case, the media companies will work with Yahoo to promote each other’s content and produce original video content for the Web.

“We’re introducing a new way to welcome people to Yahoo,” Ms. Mayer said.

But it’s more than aesthetics. Ms. Mayer is betting that the renewed focus on Yahoo’s products will turn around the company’s ailing display ad revenue. Yahoo, once the biggest seller of display ads in the United States, went from a leading 15.5 percent share of all digital ad revenues in the United States in 2009, to an 8.4 percent share last year, even as total digital ad spending grew, according to eMarketer. Meanwhile, its competitor, Google, increased its share to 41 percent.

Last month, she told analysts, “More personalized content and increased product innovation will be key to getting us back to the path for display revenue growth.”

Read More..

Well: Effects of Bullying Last Into Adulthood, Study Finds

Victims of bullying at school, and bullies themselves, are more likely to experience psychiatric problems in childhood, studies have shown. Now researchers have found that elevated risk of psychiatric trouble extends into adulthood, sometimes even a decade after the intimidation has ended.

The new study, published in the journal JAMA Psychiatry on Wednesday, is the most comprehensive effort to date to establish the long-term consequences of childhood bullying, experts said.

“It documents the elevated risk across a wide range of mental health outcomes and over a long period of time,” said Catherine Bradshaw, an expert on bullying and a deputy director of the Center for the Prevention of Youth Violence at Johns Hopkins University, which was not involved in the study.

“The experience of bullying in childhood can have profound effects on mental health in adulthood, particularly among youths involved in bullying as both a perpetuator and a victim,” she added.

The study followed 1,420 subjects from Western North Carolina who were assessed four to six times between the ages of 9 and 16. Researchers asked both the children and their primary caregivers if they had been bullied or had bullied others in the three months before each assessment. Participants were divided into four groups: bullies, victims, bullies who also were victims, and children who were not exposed to bullying at all.

Participants were assessed again in young adulthood — at 19, 21 and between 24 and 26 — using structured diagnostic interviews.

Researchers found that victims of bullying in childhood were 4.3 times more likely to have an anxiety disorder as adults, compared to those with no history of bullying or being bullied.

Bullies who were also victims were particularly troubled: they were 14.5 times more likely to develop panic disorder as adults, compared to those who did not experience bullying, and 4.8 times more likely to experience depression. Men who were both bullies and victims were 18.5 times more likely to have had suicidal thoughts in adulthood, compared to the participants who had not been bullied or perpetuators. Their female counterparts were 26.7 times more likely to have developed agoraphobia, compared to children not exposed to bullying.

Bullies who were not victims of bullying were 4.1 times more likely to have antisocial personality disorder as adults than those never exposed to bullying in their youth.

The effects persisted even after the researchers accounted for pre-existing psychiatric problems or other factors that might have contributed to psychiatric disorders, like physical or sexual abuse, poverty and family instability.

“We were actually able to say being a victim of bullying is having an effect a decade later, above and beyond other psychiatric problems in childhood and other adversities,” said William E. Copeland, lead author of the study and an associate professor of psychiatry and behavioral sciences at Duke University Medical Center.

Bullying is not a harmless rite of passage, but inflicts lasting psychiatric damage on a par with certain family dysfunctions, Dr. Copeland said. “The pattern we are seeing is similar to patterns we see when a child is abused or maltreated or treated very harshly within the family setting,” he said.

One limitation of the study is that bullying was not analyzed for frequency, and the researchers’ assessment did not distinguish between interpersonal and overt bullying. It only addressed bullying at school, not in other settings.

Most of what experts know about the effects of bullying comes from observational studies, not studies of children followed over time.

Previous research from Finland, based on questionnaires completed on a single occasion or on military registries, used a sample of 2,540 boys to see if being a bully or a victim at 8 predicted a psychiatric disorder 10 to 15 years later. The researchers found frequent bully-victims were at particular risk of adverse long-term outcomes, specifically anxiety and antisocial personality disorders. Victims were at greater risk for anxiety disorders, while bullies were at increased risk for antisocial personality disorder.

Read More..

Well: Effects of Bullying Last Into Adulthood, Study Finds

Victims of bullying at school, and bullies themselves, are more likely to experience psychiatric problems in childhood, studies have shown. Now researchers have found that elevated risk of psychiatric trouble extends into adulthood, sometimes even a decade after the intimidation has ended.

The new study, published in the journal JAMA Psychiatry on Wednesday, is the most comprehensive effort to date to establish the long-term consequences of childhood bullying, experts said.

“It documents the elevated risk across a wide range of mental health outcomes and over a long period of time,” said Catherine Bradshaw, an expert on bullying and a deputy director of the Center for the Prevention of Youth Violence at Johns Hopkins University, which was not involved in the study.

“The experience of bullying in childhood can have profound effects on mental health in adulthood, particularly among youths involved in bullying as both a perpetuator and a victim,” she added.

The study followed 1,420 subjects from Western North Carolina who were assessed four to six times between the ages of 9 and 16. Researchers asked both the children and their primary caregivers if they had been bullied or had bullied others in the three months before each assessment. Participants were divided into four groups: bullies, victims, bullies who also were victims, and children who were not exposed to bullying at all.

Participants were assessed again in young adulthood — at 19, 21 and between 24 and 26 — using structured diagnostic interviews.

Researchers found that victims of bullying in childhood were 4.3 times more likely to have an anxiety disorder as adults, compared to those with no history of bullying or being bullied.

Bullies who were also victims were particularly troubled: they were 14.5 times more likely to develop panic disorder as adults, compared to those who did not experience bullying, and 4.8 times more likely to experience depression. Men who were both bullies and victims were 18.5 times more likely to have had suicidal thoughts in adulthood, compared to the participants who had not been bullied or perpetuators. Their female counterparts were 26.7 times more likely to have developed agoraphobia, compared to children not exposed to bullying.

Bullies who were not victims of bullying were 4.1 times more likely to have antisocial personality disorder as adults than those never exposed to bullying in their youth.

The effects persisted even after the researchers accounted for pre-existing psychiatric problems or other factors that might have contributed to psychiatric disorders, like physical or sexual abuse, poverty and family instability.

“We were actually able to say being a victim of bullying is having an effect a decade later, above and beyond other psychiatric problems in childhood and other adversities,” said William E. Copeland, lead author of the study and an associate professor of psychiatry and behavioral sciences at Duke University Medical Center.

Bullying is not a harmless rite of passage, but inflicts lasting psychiatric damage on a par with certain family dysfunctions, Dr. Copeland said. “The pattern we are seeing is similar to patterns we see when a child is abused or maltreated or treated very harshly within the family setting,” he said.

One limitation of the study is that bullying was not analyzed for frequency, and the researchers’ assessment did not distinguish between interpersonal and overt bullying. It only addressed bullying at school, not in other settings.

Most of what experts know about the effects of bullying comes from observational studies, not studies of children followed over time.

Previous research from Finland, based on questionnaires completed on a single occasion or on military registries, used a sample of 2,540 boys to see if being a bully or a victim at 8 predicted a psychiatric disorder 10 to 15 years later. The researchers found frequent bully-victims were at particular risk of adverse long-term outcomes, specifically anxiety and antisocial personality disorders. Victims were at greater risk for anxiety disorders, while bullies were at increased risk for antisocial personality disorder.

Read More..

American Executive Lashes Out at French Unions, Touching Off Uproar





PARIS — “How stupid do you think we are?”




With those choice words, and several more similar in tone, the chief executive of an American tire company touched off a furor in France on Wednesday as he responded to a government plea to take over a Goodyear factory slated for closure in northern France.


“I have visited the factory a couple of times,” Maurice Taylor Jr., the head of Titan International, wrote to the country’s industry minister, Arnaud Montebourg, in a letter published in French newspapers on Wednesday. “The French work force gets paid high wages but works only three hours. They have one hour for their breaks and lunch, talk for three and work for three.“


“I told this to the French unions to their faces and they told me, ‘That’s the French way!’ ” added Mr. Taylor, a swaggering businessman who is nicknamed “the Grizz” by Wall Street analysts for his abrasive negotiating style.


His decidedly undiplomatic assessment quickly struck a nerve in France, where concerns about declining competitiveness and the divisive tax policies of President François Hollande’s government have led some economists to ask whether the nation is at risk of becoming the next sick man of Europe.


Mr. Montebourg, who is known for lashing out at French corporate bosses without hesitation, initially seemed at a loss for words on how to respond to the American charge. “I do not want to harm French interests,” he said when asked about Mr. Taylor’s letter. Later, Mr. Montebourg released a letter to Mr. Taylor, calling the executive’s comments “extreme” and “insulting,” adding that they pointed to a “perfect ignorance” about France and its strengths, which continue to attract international investors.


French media outlets minced no words. “Incendiary!” “Insulting!” and “Scathing!” were just a few of the terms replayed on French newspaper Web sites and on the airwaves throughout the day. The French blogosphere lit up with hundreds of remarks condemning the “predatory“ American corporate culture that Mr. Taylor seemed to represent; other commentators who ventured to admit that there might be something to Mr. Taylor’s observations were promptly bashed.


And France’s main labor union wasted no time in weighing in.


Mickaël Wamen, the head of the Confédération Générale du Travail union at the Goodyear plant, in Amiens, said Mr. Taylor belonged in a “psychiatric ward.”


A spokesman for Mr. Taylor did not immediately respond to calls for comment. France’s 35-hour workweek, its rigid labor market and the influence that labor unions hold over the workplace have long been a source of aggravation for businesses. Last month, after a government report warning that French competitiveness was slipping, labor unions and business leaders struck a deal to overhaul swaths of the labor code, a move Mr. Hollande said was needed to burnish France’s international allure as a place to do business.


With unemployment above 10 percent and growth slowing, the government has also been desperate to avoid large-scale layoffs. Mr. Montebourg has even brandished the threat of nationalization to try to save jobs. PSA Peugeot Citroën, ArcelorMittal, Sanofi and Air France all announced big job cuts last year as Europe’s long-running debt crisis hit their bottom lines.


So it was no surprise that Mr. Montebourg approached Titan International last year to ask if it would take over the Goodyear factory, which was scheduled to close because of labor disputes and sagging profitability — a move that would threaten 1,173 jobs.


Titan had already considered taking over the Goodyear factory’s farm tire operations. But it dropped the plan in 2011 after union representatives opposed a deal, saying they suspected Titan would close production of passenger-vehicle tires if the group took over. Tensions between Mr. Taylor and the union were evident at the time in a Titan news release, which included Mr. Taylor’s observation that “only a nonbusiness person would understand the French labor rules.”


In January, Mr. Montebourg tried to entice Titan back to the negotiating table, saying he hoped unions would put “some water in their wine, that managers put some wine in their water, and that Titan would drink the wine and the water of both” and reach an accord.


But last month, as union workers protested en masse at the Amiens site, with a large police presence, Goodyear told workers it would close the plant and cut its French work force by 39 percent.


In his letter, dated Feb. 8, Mr. Taylor explained his reasons for refusing to come back to the negotiating table. “Goodyear tried for over four years to save part of the Amiens jobs that are some of the highest-paid, but the French unions and the French government did nothing but talk,” Mr. Taylor wrote.


“Sir, your letter says you want Titan to start a discussion,” he added. “How stupid do you think we are? Titan is the one with the money and the talent to produce tires. What does the crazy union have? It has the French government.“


He said his company would seek to produce cheaper tires in India or China, where he said Titan would pay the workers less than one euro an hour, and then sell the tires back to the French. He predicted that Michelin, the French tiremaker, would not be able to compete with lower prices and would have to halt production in France within five years.


“You can keep your so-called workers,” he wrote. “Titan is not interested in the Amiens factory.”


In his response, Mr. Montebourg reacted strongly to what he called Mr. Taylor’s “condemnable calculation” and noted that France and its European partners were working to stop illegal dumping of imports.


“In the meantime,” he added, “rest assured that you can count on me to have the competent government agencies survey your imported tires with a redoubled zeal.”


This article has been revised to reflect the following correction:

Correction: February 20, 2013

An earlier version of this article misstated the status of the Goodyear factory in Amiens. While it is scheduled for closure, it remains open; it is not closed. The error was repeated in a picture caption.



Read More..

Memo From Mexico City: Mexico Anticrime Plan Challenged by Unabated Violence


Dario Lopez-Mills/Associated Press


A man guarding a roadblock at the entrance to Cruz Quemada, a rural town near Ayutla in the state of Guerrero. A recent spate of violence in the area has led communities to take up arms.







MEXICO CITY — The new Mexican president, Enrique Peña Nieto, campaigned on a promise to reduce the violence spawned by the drug trade and organized crime, and to shift the talk about his nation away from cartels and killings.




But even as he rolled out a crime prevention program last week and declared it the government’s new priority, a rash of high-profile mayhem threatened to undercut his message and raise the pressure to more forcefully confront the lawlessness that bedeviled his predecessor.


The southwestern state of Guerrero, long prone to periodic eruptions of violence, has proved a challenge once again. Gang rapes of several women have occurred in and around the faded resort town of Acapulco, including an attack this month on a group from Spain that garnered worldwide headlines, and an ambush killed nine state police officers in a mountainous no-man’s land. Out of frustration that the state was not protecting them, rural towns in Guerrero have taken up arms to police themselves.


Elsewhere, grenades were set off this month near the United States Consulate in the border town of Nuevo Laredo during a battle among gangs, and 17 members of Kombo Kolombia, a folk band in northern Mexico, were kidnapped and killed last month.


The bloodshed continued despite some indications that the violence leveled off last year, according to a report released on Feb. 5 by the University of San Diego’s Trans-Border Institute, which analyzed a range of government homicide statistics. Mr. Peña Nieto’s government also released statistics this month that it said showed that homicides presumably related to organized crime had dipped from December to January, but analysts have long questioned how those numbers were compiled, given the chronic lack of criminal investigations.


Still, the appetite of criminal groups for shocking violence seems unabated and presents a challenge for the president. Can he manage to avoid being drawn into the iron-fisted approach of his predecessor and effectively change the focus of the national discussion to other matters, like the economy?


“They are trying to have the president not use the crime issue as his political priority,” said Ana Maria Salazar, a security analyst who worked in the American government and now hosts a radio show here. “But at the same time, it doesn’t seem what they are talking about is confronting or going to have an impact on the current violence and criminal organizations.”


She added, “They haven’t laid out what they are going to do in the short term to retake Mexican territory in control of criminal organizations.”


Government officials have asked for patience, saying Mexico’s crime problems cannot be solved overnight.


They have made it clear that they want to break with the approach of former President Felipe Calderón, who heavily enlisted the military and the federal police against crime gangs, but the new government has taken a similar tack in recent flare-ups, including sending a cadre of federal police officers to Acapulco after the attacks there. Government officials have pledged closer coordination between the federal police and the state authorities.


Officials are promoting the less militaristic crime prevention program introduced last week as a linchpin, with Mr. Peña Nieto personally announcing it and Interior Secretary Miguel Ángel Osorio Chong briefing reporters extensively on it. On Thursday, an under secretary presented a slick brochure on the program to foreign journalists and answered questions for 45 minutes.


“It’s clear that we must put special emphasis on prevention, because we can’t only keep employing more sophisticated weapons, better equipment, more police, a higher presence of the armed forces in the country as the only form of combating organized crime,” Mr. Peña Nieto said in announcing the program in Aguascalientes, one of the more peaceful precincts in the country.


The program calls for creating an interagency commission that would spend $9 billion in the coming years in 250 of the most violent cities and towns, beginning with the worst. The plan envisions longer school days, drug addiction programs and other social efforts in addition to public works projects, but officials said specifics were still being worked out and would be detailed later.


It resembles a plan Mr. Calderón put in place a few years ago for Ciudad Juárez, one of the bloodiest cities in Mexico, but government officials said that while they studied that project, they believed that their plan differed in ambition and scope.


Few argue with the need for such programs and alternatives to crime for young people. But security analysts faulted Mr. Calderón for not attacking corruption by building effective, accountable local and state police and judicial institutions, a herculean task that Mr. Peña Nieto so far has not shown much sign of taking on either.


This article has been revised to reflect the following correction:

Correction: February 19, 2013

An earlier version of this article referred incompletely to Chris Kyle’s academic affiliation. He is an anthropologist at the University of Alabama at Birmingham; the University of Alabama’s flagship campus is in Tuscaloosa.



Read More..

Disruptions: Disruptions: 3-D Printing Is on the Fast Track

Will the future be printed in 3-D?

At first glance, looking at past predictions about the future of technology, prognosticators got a whole lot wrong. The Web is a garbage dump of inaccurate guesses about the year 2000, 2010 and beyond. Flying cars, robotic maids and jet packs still are nowhere near a reality.

Yet the prediction that 3-D printers will become a part of our daily lives is happening much sooner than anyone anticipated. These printers can produce objects, even rather intricate ones, by printing thin layer after layer of plastic, metal, ceramics or other materials. And the products they make can be highly customized.

Last week, President Obama cited this nascent technology during his State of the Union address — as if everyone already knew what the technology was.

He expressed hope that it was a way to rejuvenate American manufacturing. “A once-shuttered warehouse is now a state-of-the art lab where new workers are mastering the 3-D printing that has the potential to revolutionize the way we make almost everything,” Mr. Obama said. He has pushed new technologies before, like solar and wind power, as remedies for our nation’s problems, and those attempts have only revived the debate about the limitations of government industrial policy.

But this one shows more promise. The question is, can the United States get a foothold in manufacturing one 3-D printer at a time?

Hod Lipson, an associate professor and the director of the Creative Machines Lab at Cornell, said “3-D printing is worming its way into almost every industry, from entertainment, to food, to bio- and medical-applications.”

It won’t necessarily directly create manufacturing jobs, except perhaps for the printers themselves. Dr. Lipson, the co-author of “Fabricated: The New World of 3D Printing,” said that the technology “is not going to simply replace existing manufacturing anytime soon.” But he said he believed that it would give rise to new businesses. “The bigger opportunity in the U.S. is that it opens and creates new business models that are based on this idea of customization.”

In addition to the lab that the president mentioned, a federally financed manufacturing innovation institute in Youngstown, Ohio, schools are embracing the technology. The University of Virginia has been working to introduce 3-D printers into some programs from kindergarten through 12th grade in Charlottesville to prepare students for a new future in manufacturing.

“We have 3-D printers in classrooms, and in one example, we’re teaching kids how to design and print catapults that they then analyze for efficiency,” said Glen L. Bull, professor and co-director of the Center for Technology and Teacher Education. “We believe that every school in America could have a 3-D printer in the classroom in the next few years.”

The education system may want to speed things up. The time between predictions for 3-D printers and the reality of what they can accomplish is compressing rapidly.

For example, in 2010, researchers at the University of Southern California said that another decade would pass before we could build a home using a 3-D printer. Yet last week, Softkill Design, a London architecture collective, announced that it planned to make the first such home — which it will assemble in a single day — later this year. The home isn’t that pretty, and will look more like a calcified spider web than a cozy house, but it will show it can be done. The price of 3-D printers has also dropped sharply over the last two years, with machines that once cost $20,000, now at $1,000 or less. That’s partly because Chinese companies are driving down prices. Yes, China sees the opportunity in these things, even though the technology may undermine some of its manufacturing advantages.

“When it costs you the same amount of manufacturing effort to make advanced robotic parts as it does to manufacture a paperweight, that really changes things in a profound way,” Dr. Lipson said.

This leaves us with one more question about the future: When will these 3-D printers be able to make us flying cars, robotic maids and jet packs?

E-mail: bilton@nytimes.com

Read More..

DNA Analysis, More Accessible Than Ever, Opens New Doors


Matt Roth for The New York Times


Sam Bosley of Frederick, Md., going shopping with his daughter, Lillian, 13, who has a malformed brain and severe developmental delays, seizures and vision problems. More Photos »







Debra Sukin and her husband were determined to take no chances with her second pregnancy. Their first child, Jacob, who had a serious genetic disorder, did not babble when he was a year old and had severe developmental delays. So the second time around, Ms. Sukin had what was then the most advanced prenatal testing.




The test found no sign of Angelman syndrome, the rare genetic disorder that had struck Jacob. But as months passed, Eli was not crawling or walking or babbling at ages when other babies were.


“Whatever the milestones were, my son was not meeting them,” Ms. Sukin said.


Desperate to find out what is wrong with Eli, now 8, the Sukins, of The Woodlands, Tex., have become pioneers in a new kind of testing that is proving particularly helpful in diagnosing mysterious neurological illnesses in children. Scientists sequence all of a patient’s genes, systematically searching for disease-causing mutations.


A few years ago, this sort of test was so difficult and expensive that it was generally only available to participants in research projects like those sponsored by the National Institutes of Health. But the price has plunged in just a few years from tens of thousands of dollars to around $7,000 to $9,000 for a family. Baylor College of Medicine and a handful of companies are now offering it. Insurers usually pay.


Demand has soared — at Baylor, for example, scientists analyzed 5 to 10 DNA sequences a month when the program started in November 2011. Now they are doing more than 130 analyses a month. At the National Institutes of Health, which handles about 300 cases a year as part of its research program, demand is so great that the program is expected to ultimately take on 800 to 900 a year.


The test is beginning to transform life for patients and families who have often spent years searching for answers. They can now start the grueling process with DNA sequencing, says Dr. Wendy K. Chung, professor of pediatrics and medicine at Columbia University.


“Most people originally thought of using it as a court of last resort,” Dr. Chung said. “Now we can think of it as a first-line test.”


Even if there is no treatment, there is almost always some benefit to diagnosis, geneticists say. It can give patients and their families the certainty of knowing what is wrong and even a prognosis. It can also ease the processing of medical claims, qualifying for special education services, and learning whether subsequent children might be at risk.


“Imagine the people who drive across the whole country looking for that one neurologist who can help, or scrubbing the whole house with Lysol because they think it might be an allergy,” said Richard A. Gibbs, the director of Baylor College of Medicine’s gene sequencing program. “Those kinds of stories are the rule, not the exception.”


Experts caution that gene sequencing is no panacea. It finds a genetic aberration in only about 25 to 30 percent of cases. About 3 percent of patients end up with better management of their disorder. About 1 percent get a treatment and a major benefit.


“People come to us with huge expectations,” said Dr. William A. Gahl, who directs the N.I.H. program. “They think, ‘You will take my DNA and find the causes and give me a treatment.' ”


“We give the impression that we can do these things because we only publish our successes,” Dr. Gahl said, adding that when patients come to him, “we try to make expectations realistic.”


DNA sequencing was not available when Debra and Steven Sukin began trying to find out what was wrong with Eli. When he was 3, they tried microarray analysis, a genetic test that is nowhere near as sensitive as sequencing. It detected no problems.


“My husband and I looked at each other and said, ‘The good news is that everything is fine; the bad news is that everything is not fine,' ” Ms. Sukin said.


In November 2011, when Eli was 6, Ms. Sukin consulted Dr. Arthur L. Beaudet, a medical geneticist at Baylor.


“Is there a protein missing?” she recalled asking him. “Is there something biochemical we could be missing?”


By now, DNA sequencing had come of age. Dr. Beaudet said that Eli was a great candidate, and it turned out that the new procedure held an answer.


A single DNA base was altered in a gene called CASK, resulting in a disorder so rare that there are fewer than 10 cases in all the world’s medical literature.


“It really became definitive for my husband and me,” Ms. Sukin said. “We would need to do lifelong planning for dependent care for the rest of his life.”


This article has been revised to reflect the following correction:

Correction: February 19, 2013

An earlier version of this article misstated the name of a medicine taken by two teenagers who have a rare gene mutation. The drug is 5-hydroxytryptophan, not 5-hydroxytryptamine.



Read More..

DNA Analysis, More Accessible Than Ever, Opens New Doors


Matt Roth for The New York Times


Sam Bosley of Frederick, Md., going shopping with his daughter, Lillian, 13, who has a malformed brain and severe developmental delays, seizures and vision problems. More Photos »







Debra Sukin and her husband were determined to take no chances with her second pregnancy. Their first child, Jacob, who had a serious genetic disorder, did not babble when he was a year old and had severe developmental delays. So the second time around, Ms. Sukin had what was then the most advanced prenatal testing.




The test found no sign of Angelman syndrome, the rare genetic disorder that had struck Jacob. But as months passed, Eli was not crawling or walking or babbling at ages when other babies were.


“Whatever the milestones were, my son was not meeting them,” Ms. Sukin said.


Desperate to find out what is wrong with Eli, now 8, the Sukins, of The Woodlands, Tex., have become pioneers in a new kind of testing that is proving particularly helpful in diagnosing mysterious neurological illnesses in children. Scientists sequence all of a patient’s genes, systematically searching for disease-causing mutations.


A few years ago, this sort of test was so difficult and expensive that it was generally only available to participants in research projects like those sponsored by the National Institutes of Health. But the price has plunged in just a few years from tens of thousands of dollars to around $7,000 to $9,000 for a family. Baylor College of Medicine and a handful of companies are now offering it. Insurers usually pay.


Demand has soared — at Baylor, for example, scientists analyzed 5 to 10 DNA sequences a month when the program started in November 2011. Now they are doing more than 130 analyses a month. At the National Institutes of Health, which handles about 300 cases a year as part of its research program, demand is so great that the program is expected to ultimately take on 800 to 900 a year.


The test is beginning to transform life for patients and families who have often spent years searching for answers. They can now start the grueling process with DNA sequencing, says Dr. Wendy K. Chung, professor of pediatrics and medicine at Columbia University.


“Most people originally thought of using it as a court of last resort,” Dr. Chung said. “Now we can think of it as a first-line test.”


Even if there is no treatment, there is almost always some benefit to diagnosis, geneticists say. It can give patients and their families the certainty of knowing what is wrong and even a prognosis. It can also ease the processing of medical claims, qualifying for special education services, and learning whether subsequent children might be at risk.


“Imagine the people who drive across the whole country looking for that one neurologist who can help, or scrubbing the whole house with Lysol because they think it might be an allergy,” said Richard A. Gibbs, the director of Baylor College of Medicine’s gene sequencing program. “Those kinds of stories are the rule, not the exception.”


Experts caution that gene sequencing is no panacea. It finds a genetic aberration in only about 25 to 30 percent of cases. About 3 percent of patients end up with better management of their disorder. About 1 percent get a treatment and a major benefit.


“People come to us with huge expectations,” said Dr. William A. Gahl, who directs the N.I.H. program. “They think, ‘You will take my DNA and find the causes and give me a treatment.' ”


“We give the impression that we can do these things because we only publish our successes,” Dr. Gahl said, adding that when patients come to him, “we try to make expectations realistic.”


DNA sequencing was not available when Debra and Steven Sukin began trying to find out what was wrong with Eli. When he was 3, they tried microarray analysis, a genetic test that is nowhere near as sensitive as sequencing. It detected no problems.


“My husband and I looked at each other and said, ‘The good news is that everything is fine; the bad news is that everything is not fine,' ” Ms. Sukin said.


In November 2011, when Eli was 6, Ms. Sukin consulted Dr. Arthur L. Beaudet, a medical geneticist at Baylor.


“Is there a protein missing?” she recalled asking him. “Is there something biochemical we could be missing?”


By now, DNA sequencing had come of age. Dr. Beaudet said that Eli was a great candidate, and it turned out that the new procedure held an answer.


A single DNA base was altered in a gene called CASK, resulting in a disorder so rare that there are fewer than 10 cases in all the world’s medical literature.


“It really became definitive for my husband and me,” Ms. Sukin said. “We would need to do lifelong planning for dependent care for the rest of his life.”


This article has been revised to reflect the following correction:

Correction: February 19, 2013

An earlier version of this article misstated the name of a medicine taken by two teenagers who have a rare gene mutation. The drug is 5-hydroxytryptophan, not 5-hydroxytryptamine.



Read More..

DealBook: Einhorn Has Edge in Dispute With Apple

In the battle between Apple and David Einhorn, score a point for the hedge fund manager.

A federal judge said on Tuesday that he was leaning toward Mr. Einhorn’s contention in a lawsuit that the iPad maker violated securities regulations by improperly bundling several shareholder proposals into one matter.

The lawsuit by Mr. Einhorn’s Greenlight Capital, filed in Federal District Court in Manhattan, claims that Apple unjustly tied a vote to eliminate the company’s ability to issue preferred stock at will with other initiatives that the hedge fund manager supports.

While the judge overseeing the case, Richard J. Sullivan, didn’t immediately grant Mr. Einhorn’s request for an halt to the vote, he said that the facts of the case favored the investor’s interpretation.

“I think success on the merits lies with Greenlight,” Judge Sullivan said at the end of a two-hour hearing.

He is expected to decide whether to grant a preliminary injunction within days, citing the Feb. 27 cutoff for voting on Apple’s shareholder proposals.

Read More..